Education & Resources
The following are some common terms used in our practice.
Prolotherapy is the injection of a substance (i.e. Dextrose) which promotes growth of normal cells. Pain and dysfunction is often caused by weakened tendons, ligaments and soft tissues. These weakened structures can be healed and strengthened by a series of injections of this substance (i.e. Dextrose) into them. These injections invoke the body’s natural healing response to strengthen the tissues and structures without causing the harmful effects that steroids cause. In effect, the pain decreases or completely goes away and the function of the joint/structure improves.
Prolotherapy is an injection technique used to heal injuries that aren’t healing correctly including sports injuries and chronic injuries. Prolotherapy does not cover up the symptoms of the injury for a temporary fix. It gets to the heart of the issue to permanently fix the injured area. It is used widely in athletes and chronic pain patients. Pain from athletic injuries, motor vehicle accidents, whiplash injuries and headaches, sprains/strains, chronic neck/back/joint pain and overuse injuries are treated with Prolotherapy.
Used by many professional and amateur athletes, prolotherapy is also known as non-surgical ligament reconstruction and is a permanent treatment for chronic pain. Ligaments are what hold bones together at the joint, whether in the knee or the back or other body area. When they are injured, these tight rubber bands that keep the joint together become loose and the joint loses its integrity. This causes pain. The poor blood supply to the ligaments makes it hard for them to heal and they often do not which leads to this chronic pain.
Perineural Therapy (Lyftogt technique)
Perineural therapy is used for nerve pain or chronic structural pain. It is a series of injections of a natural substance (i.e. mannitol or dextrose) superficially into the skin to target painful nerves. Weekly visits reduce the pain and help you to return to full function.
Traumeel is a safe anti-inflammatory alternative to steroids that’s been used in the United States since 1986 and in Europe since 1937. There is no evidence of the “rebound effect” (inflammation returning to a greater degree than prior treatment), which is often experienced with steroid use.
Prolo- means to regenerate and is short for proliferation, because the treatment causes the proliferation (growth, formation) of new ligament tissue in areas where it has become weak. This causes the ligaments to become strong again and keep the joint properly intact. The pain and dysfunction then goes away as the problem is now fixed. The response to treatment varies from patient to patient, and depends upon one’s healing ability. Some people may only need a few treatments while others may need 6-8. These treatments are done at 4-6 weeks intervals.
Platelet Rich Plasma (PRP)
Platelet Rich Plasma (PRP): A new procedure that is gaining popularity across the world in the treatment of tendinopathies and arthropathies is platelet rich plasma administration. This procedure is analogous to autologous blood injections, but involves delivery of the concentrated platelet rich plasma, which is rich in growth factors.
Blood platelets are responsible for bringing white blood cells to the injured area to clean up the remains of dead and injured cells. Most importantly to this discussion, blood platelets release growth factors that are directly responsible for tissue regeneration. These substances are called cytokines and include platelet derived growth factor, epithelial growth factor, and other important growth factors.
PRP has been used for years in surgical centers around the US and abroad to improve the success of bone grafting (especially in dental surgery) and also by cosmetic surgeons for speeding healing time and decreasing the risk of infection after surgery. Only in the last few years have doctors and surgeons been experimenting with injecting PRP for the treatment of chronic pain. Tennis elbow, plantar fasciitis, achilles tendonitis/tendonosis, rotator cuff tears, meniscal tears, osteoarthritis and chronic low back and neck pain are all being treated with the injection of PRP with the goal of regenerating degenerated connective tissue with reports of success.
View our library of educational videos.
Dr. Tricia Croake-Uleman, M.D. on “Fitness Focus” – Prolotherapy for Hips
Dr. Tricia Croake-Uleman, M.D. on “Fitness Focus” – Prolotherapy for Knees
Dr. Tricia Croake-Uleman, M.D. on “Fitness Focus” – Prolotherapy for Shoulders
Dr. Fields on “The Doctors” TV Show – Prolotherapy
How long does prolotherapy last?
Dr. Marc Darrow – Prolotherapy performed on the knee
Does the healing from Prolotherapy last?
Who would be a candidate for Prolotherapy?
Prolotherapy segment on “Fox 59 Indianapolis”
- Marx RE, Garg AK. Dental and Craniofacial Applications of Platelet-Rich Plasma. 2005. Quintessence Publishing. Chicago.
- Sampson S, Gerhardt M, Mandelbaum B. Platelet rich plasma injection grafts for musculoskeletal injuries: a review. 2008. Curr Rev Musculoskeletal Med. DOI 10.1007/s12178-008-9032-5
- Mishra A, Pavelko T. Treatment of chronic elbow tendinosis with buffered platelet rich plasma. 2006. Am J Sports Med. 34, 1774-8.
- How can one platelet injection after tendon injury lead to a stronger tendon after 4 weeks? by Olena Virchenko and Per Aspenberg
Clinical Updates in Platelet Gel: Sports Medicine by Michael A. Scarpone D.O.
Non-Surgical Repair of Patellar Tendonitis with Autologous Platelet Concentrate Using Ultrasound Guidance:Two Case Reports by Henry Stiene M.D.
Autologous Blood Injection for the Treatment of Chronic Recurrent Temporomandibular Joint Dislocation by Vladimir Machon M.D., D.M.D., Shelly Abramowicz D.M.D., M.P.H., Jan Paska M.D. and M. Franklin Dolwick D.M.D., Ph.D.
Treatment of Chronic Elbos Tendinosis with Buffered Platelet-Rich Plasma by Allan Mishra M.D. and Terri Pavelko P.A.C., P.T
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